정보공개
삼채의 급여가 제 2형 당뇨마우스의 지질대사에 미치는 영향
- 작성일2017.05.15 00:00
- 분류
- 조회수1,948
- 링크http://kiss.kstudy.com/journal/thesis_name.asp?tname=kiss2002&key=3338477
- 저널명생약학회지
- 저자이선혜,김남석,최봉겸,이성현,장환희,김정봉,이영민,김대근,이창현,김유석,양재헌,김영수,김현주
- 구분
- 유형
제목
삼채의 급여가 제 2형 당뇨마우스의 지질대사에 미치는 영향
요약
Allium hookeri is a plant species native to India, Sri Lanka, Myanmar, and China. The plant is widely cultivated in Korea lately as a medicinal food item. This study was conducted to evaluate the effects of Allium hookeri (A. hookeri) on lipid metabolism in Type II diabetic mice (n=8/group, 5 groups). High fat diets with dextrin as a positive control (Dex), leaf (AL), root (AR), and fermented root (FAR) at 3% of diet were fed to all experimental mouse, respectively for 8 weeks. Body weight gain, liver and epididymal fat weights, and excreted fecal lipid levels were measured. Serum and hepatic lipid profiles were analyzed, and fat accumulation in liver was evaluated. In this study, body weight gain and epididymal fat weight were lower in the FAR group, while serum HDL-cholesterol level and excreted fecal total lipid and triglyceride levels were higher in AL or FAR groups. These results suggest that A. hookeri, specially fermented root can be a useful food item to control lipid metabolism in diabetic mice.
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