연구분야
Antibacterial activities of penicillic acid isolated from Aspergillus persii against various plant p
- 작성일2017.05.15 00:00
- 분류
- 조회수1,730
- 링크http://onlinelibrary.wiley.com/doi/10.1111/lam.12578/pdf
- 저널명Letters in Applied Microbiology
- 저자H.T. Nguyen,유난희,김진철,전선정,이혜원,배창환,여주홍,이향범,김인선,박해웅
- 구분
- 유형
제목
Antibacterial activities of penicillic acid isolated from Aspergillus persii against various plant pathogenic bacteria
요약
The emergence of pathogenic bacterial strains resistant to agrochemicals and the increasing demand for organic foods have led to the discovery of new antibacterial metabolites that can be used either directly or as a lead molecule for development of synthetic bactericides. During the screening of antibacterial fungal cultures, we found that one fungal strain, Aspergillus persii EML-HPB111, showed strong in vitro antibacterial activity against Xanthomonas arboricola pv. pruni (Xap) with a minimum inhibitory concentration (MIC) of 10% of fermentation broth ?ltrate. The active compound was identi?ed as penicillic acid (PA: 3-methoxy-5-methyl-4-oxo-2,5-hexadienoic acid) by mass and NMR spectroscopy. The in vitro antibacterial activity of PA was tested against 12 phytopathogenic bacteria. All of the bacterial pathogens tested were highly inhibited by PA with MIC values of 123?1111 lg ml 1. It also effectively suppressed the development of bacterial spot disease in detached peach leaves, showing control values of 824 and 941% at concentrations of 1111 and 3333 lg ml 1 respectively. This is the ?rst report on the production of PA by A. persii. This study suggests that PA can be used as a lead molecule for development of synthetic bactericides for control of various plant diseases.
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