아질산염 소거 작용을 가진 산채 혼합물을 함유한 김치의 황산화 활성 및 산화적 신경세포 사멸 억제 효과

제목

아질산염 소거 작용을 가진 산채 혼합물을 함유한
김치의 황산화 활성 및 산화적 신경세포 사멸
억제 효과

요약

This study was carried out to investigate the nitrite scavenging activities (NSA) of nine kinds of wild

vegetables in a NaNO

model system and nitrite of Chinese cabbage as well as the inhibitory effect of kimchi containing

a mixture of wild vegetables (MWV) with nitrite scavenging activity on brain neuronal cell death. NSA was higher

at pH 1.2 than pH 4.2 in all samples. NSA of extracts from sprouts of Oenothera laciniata and Aster scaber (AS)

was above 90% at pH 1.2. AS, Codonopsis lanceolate (CL), Adenophora triphylla (AT), Platycodon grandiflorum

(PG), and Taraxacum officinale (TO) extracts showed significantly higher levels of NSA than those from other extracts

at pH 4.2. CL, AT, PG, and TO extracts showed high NSA on nitrite of Chinese cabbage. In addition, the effects

of MWV on antioxidant and brain neuronal cell death induced by oxidative stress were investigated in human brain

neuroblastoma SK-N-SH cells. MWV extract attenuated H

-induced cell death and reactive oxygen species (ROS)

generation in SK-N-SH cells. MWV extract showed significantly higher DPPH radical scavenger activity when compared

to normal kimchi extract. MWV extract showed an inhibitory effect on brain neuronal cell death against oxidative

stress by antioxidant activities

주요알림